Respiration Issues. Promethazine/codeine could bring about sluggish or shallow respiratory, particularly when you might have respiration troubles from One more issue or acquire other medicines which can slow your respiration.
Your healthcare company may possibly do blood assessments to check for adrenal gland complications. Phone your healthcare supplier right away In case you have any of those signs and symptoms:
Tend not to consume Liquor or use prescription or above-the-counter medicines that have alcohol. Using Alcoholic beverages when using promethazine/codeine can result in you to overdose and die.
Will not share promethazine/codeine with Other individuals, regardless of whether they've a similar problem when you. It might hurt them.
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Life-threatening respiratory melancholy and death have transpired in kids who been given codeine; most instances followed tonsillectomy and/or adenoidectomy, and lots of of the children had evidence of currently being an ultra-speedy metabolizer of codeine as a consequence of a CYP2D6 polymorphism. (five.3) Promethazine HCl and Codeine Phosphate Oral Answer is contraindicated in young children young than 12 many years of age As well as in young children young than eighteen years of age pursuing tonsillectomy and/or adenoidectomy.
On the other hand, codeine must be administered only beneath shut supervision to patients with a historical past of drug abuse or dependence.
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Hazard of Misuse and Habit. Misusing promethazine/codeine can cause significant Unwanted effects like coma or death. Misuse means getting a medicine in a way other than how it was prescribed.
Phenothiazines are involved with dystonic reactions, especially in pediatric clients who have an acute ailment linked with dehydration. Paradoxical reactions, which include dystonia, torticollis, tongue protrusion, get more info hyperexcitability, and irregular movements are already reported in clients adhering to a single administration of promethazine. Discontinue Promethazine HCl and Codeine Phosphate Oral Alternative if a paradoxical reaction takes place.
Breastfeeding. Tend not to just take promethazine/codeine website while you're breastfeeding. Promethazine/codeine can go into breast milk. Inform your Health care supplier if you are read more breastfeeding or plan to breastfeed.
Before working with this medication, Girls of childbearing age must talk with their health care provider(s) about the threats and Positive aspects. Inform your health care provider When you are pregnant or Imagine you might be Expecting. For the duration of pregnancy, this medication is not advisable. It might marginally enhance the chance of birth defects if utilised in the initial two months of pregnancy. Also, utilizing it for a very long time or in high doses near the predicted supply date may possibly hurt the unborn baby.
長期使用時，身體可對可待因產生耐藥性，令藥效減弱，並有可能產生依賴性。